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Hemophilia is a genetically transmitted, life-threatening, chronic bleeding disorder, which can disable the affected person if left untreated. In rare cases, a person can develop hemophilia later in life. The majority of cases involve middle-aged or elderly people, or young women who have recently given birth or are in the later
stages of pregnancy. Acquired hemophilia is usually caused by the development of antibodies to factor VIII (the body’s immune system destroys its own naturally produced factor VIII). This condition often resolves with appropriate treatment, which typically involves a combination of steroid treatment and the drug Cyclophosphamide.
    • There are two types of Hemophilia: Hemophilia A (Classical hemophilia) and Hemophilia B (Christmas disease).
    • Hemophilia A is caused by deficiency of factor VIII, and hemophilia B is caused by deficiency of factor IX.
  • People with severe Hemophilia usually bleed frequently into their muscles or joints. They may bleed one or two times per week. Bleeding is often spontaenous, which means the bleeding just happened with no obvious cause.
  • People with moderate hemophilia bleed less frequently, usually after an injury, perhaps once a month. Cases of hemophilia vary, however, and a person with moderate hemophilia can bleed spontaneously.
  • People with mild hemophilia usually bleed only as a result of surgery or major injury. They may never have a bleeding problem.

 

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